Protein Sequence by Bioinformatics Methods - Hypothetical Protein - Bioinformatics Assignment Help

Download Solution Now
  • Internal Code :

    1BEFEA

  • Country :

    Australia

Connect with Assignment Expert Now

Assignment Task:

Introduction:
You are required to analyse a protein sequence by bioinformatics methods. What is its likely function? If it does not have a structure can you determine a model for the structure? What does the model tell you about its function? It might also be a "hypothetical" protein, where the structure has already been determined by a structural genomics consortium. In which case can you use sequence and known structure to determine protein function? You are not restricted to methods covered in the lectures, but you should focus on methods with the general aim of prediction of protein function and/or structure from sequence. You can either request a sequence to the module manager or chose your own.

Questions you might want to think about before choosing a protein:

1. Use this assessment to do an in-depth analysis of a protein (or protein family) that interests you and/or for which there is an interesting biological question.

2. Use it to pull out new protein family members (e.g. to those of a well-characterized family of proteins) that are not found by BLAST/FASTA.

3. Use it to try out some new tools that we were unable to cover in the course. 

4. Use it to increase your depth of knowledge of tools that we have covered in the course e.g. structure prediction methods (comparative modelling or fold recognition) and try to relate the structure you get to its known function - e.g. active site, binding site etc. 

5. Use it to study a protein that has recently appeared in the scientific press (Nature, Science, New Scientist) or even the daily press! If it is not already highly characterized (and in some cases, it may well be) then there may be an interesting bioinformatics story to be told or new and different analyses that can be done. 

6. If you are interested in the protein family then there are family tools we have looked at (ClustalW, JalView Pfam). 

7. If you are interested in finding new proteins related to your protein of interest in other organisms then PSI-BLAST and Hidden Markov techniques such as HMMER or SAM may be useful

8. If you have a transmembrane spanning protein- there are programs you can use to predict TM helices etc. (e.g. TMpred, Memsat, DAS etc.)

Do you need to get structural information in order to answer the biological questions you are asking? If so you should check either you can make a comparative model OR get meaningful information from fold recognition before you proceed with your chosen protein.


This Bioinformatics Assignment has been solved by our Bioinformatics Experts at TV Assignment Help. Our Assignment Writing Experts are efficient to provide a fresh solution to this question. We are serving more than 10000+ Students in Australia, UK & US by helping them to score HD in their academics. Our experts are well trained to follow all marking rubrics & referencing style.

Be it a used or new solution, the quality of the work submitted by our assignment experts remains unhampered. You may continue to expect the same or even better quality with the used and new assignment solution files respectively. There’s one thing to be noticed that you could choose one between the two and acquire an HD either way. You could choose a new assignment solution file to get yourself an exclusive, plagiarism (with free Turnitin file), expert quality assignment or order an old solution file that was considered worthy of the highest distinction.

  • Uploaded By : Alex Cerry
  • Posted on : January 29th, 2019
  • Downloads : 0

Download Solution Now

Review Question

Please enter your email

Can't find what you're looking for?

Why are you waiting for Assignment Deadline?
Book Assignment Today & Get 500 Words Free
Order Now TnC Apply
cancel question

Choose a Plan

Premium

80 USD
  • All in Gold, plus:
  • 30-minute live one-to-one session with an expert
    • Understanding Marking Rubric
    • Understanding task requirements
    • Structuring & Formatting
    • Referencing & Citing
Most
Popular

Gold

30 50 USD
  • Get the Full Used Solution
    (Solution is already submitted and 100% plagiarised.
    Can only be used for reference purposes)
Save 33%

Silver

20 USD
  • Journals
  • Peer-Reviewed Articles
  • Books
  • Various other Data Sources – ProQuest, Informit, Scopus, Academic Search Complete, EBSCO, Exerpta Medica Database, and more