Internal Code: MAS517
Diabetes mellitus is a major world health problem. Treatment and management of diabetics is a very
significant issue for governments, society and both pharmacists and pharmaceutical companies. Completing this assignment will help you to gain a deeper understanding of diabetes mellitus.
1. Why is the disease given the name diabetes mellitus? How does diabetes mellitus differ from
2. Individuals with the diabetes mellitus are classified into two main groups. What are they and
what is the basis of the classification system used?
3. How are patients diagnosed as diabetics? What treatment options are most used to manage this
4. What changes in the metabolism of glucose and fat (triglycerides) are observed in this disease?
What symptoms might a diabetic show as a result of these metabolic changes and why do these
5. Two overnight fasting patients, A & B, were each given a dose of 75g of glucose at time zero.
Their blood glucose levels were measured at 0, 30, 60, 90, 120 and 240 minutes after ingestion of the glucose using a glucose specific assay. The brief procedure for this assay is:-
a. Add 5.0 ml of assay reagent to sufficient tubes for the assay
b. Add 0. 1 ml of each glucose standard to a tube of assay reagent
c. Add 0. 1 ml of each test serum to a tube of assay reagent.
d. Mix the contents of each tube and read the absorbance at 625 nm.
Determine the concentration of glucose in each patient serum sample and plot glucose concentration against the time over which the samples were obtained.
6. What potential long term problems would a pharmacist need to be aware of when advising a diabetic client?
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