University : University of Central Lancashire UniLearnO is not sponsored or endorsed by this college or university.
Subject Code : ER4120
Country : United Kingdom
Assignment Task:

Learning outcomes

The assignment should produce sufficient evidence for partial fulfillment of the following module learning outcomes:
• Solve specific research informed design problems associated with integrated mechanical engineering systems.
• Develop comprehensive design processes and methodologies and adapt them to unfamiliar research informed situations.
• Demonstrate high level competencies in the use of computational modelling tools used in highly technical industries and academic research.

1 Background 
Arteries are blood vessels that carry blood from the heart to the rest of the body and the heart muscle. Arterial thrombosis is a blood clot in an artery, which can can stop blood reaching important organs. This can cause several serious health problems, including: heart attack, stroke, Transient Ischaemic Attack (TIA) and critical limb ischaemia. It has been shown by researchers in the John Tyndall Institute at the University of Lancashire that the risk of arterial thrombosis, particularly micro-anastomostic repair, is increased in then presence of unnaturally high Shear Strain Rates (SSRs). Moreover, according to a forthcoming PhD thesis [1] to be submitted within the John Tyndall Institute:

Blood is a suspension of various solid cells in a liquid plasma, formed from a solution of proteins and minerals. The rheological properties of blood are influenced by individual characteristics of these com- ponents as well as factors such as haematocrit, amongst others [2]. Whilst plasma itself is a Newtonian fluid, addition of the blood cellular components alters its rheological behaviour towards that of a shear- thinning non-Newtonian fluid [2]. Nevertheless, opinions vary in the existing literature as to how best to simulate blood rheology [3]. Furthermore, whilst numerous models relating effective viscosity to shear rate have been described and studied, great inconsistencies exist in the literature between their nomenclature and parameters [4, 5]. 

Non-Newtonian Blood Flow Modelling representation of Sisko non-Newtonian flow

Computational Mechanics


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  • Posted on : April 27th, 2019
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